Mahasin A. Osman, Msc. Ph.D.听鈥� Publications
Selected articles
The IQGAP1-Claudin4-JNK Signaling Axis as a Differential Biomarker in Renal Cell Carcinoma
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First published: 15 April 2026听
The IQGAP1-claudin cell junction axis in cisplatin-induced epithelial damage.听Cell Commun Signal (2026).
Preprint: Yusuf Barudi, Xiuzhen Fan, Kenneth W Jenkins III, Shubhra Kanti Dey, Evgeny Yakirevich, Mahasin A. Osman. . bioRxiv 2024.12.21.629915; doi: https://doi.org/10.1101/2024.12.21.629915
Iyer VJ, Donahue JE, Osman MA. Role of scaffold proteins in the heterogeneity of glioblastoma. Cell Commun Signal. 2024 Oct 7;22(1):477. doi: 10.1186/s12964-024-01809-1. PMID: 39375741; PMCID: PMC11457365.
Iyer, Varun J., John E. Donahue, Mahasin A. Osman (2024) Role of scaffold proteins in the heterogeneity of glioblastoma. 听Springer Nature, Cell Communication and Signaling. DOI 86a10bfe-62d1-4835-8fcc-da2f5785dc5. In press
Sahay S, Hamoud A-r, Osman M, Pulvender P, McCullumsmith RE. Expression of WNT Signaling Genes in the Dorsolateral Prefrontal Cortex in Schizophrenia.听Brain Sciences. 2024; 14(7):649. https://doi.org/10.3390/brainsci14070649
Robinson TS, Osman MA. An Emerging Role for Sigma Receptor 1 in Personalized Treatment of Breast Cancer. Cancers (Basel). 2023 Jul 2;15(13):3464. doi: 10.3390/cancers15133464. PMID: 37444574; PMCID: PMC10340381.
Iyer VJ, Osman MA (2023). The Antipsychotic Drug Haldol Modulates IQGAP1-Signaling and Inhibits Cell Proliferation in Triple Negative Breast Cancer Cell Lines. MicroPubl Biol. 2023 May 5;2023:10.17912/micropub.biology.000823. doi: 10.17912/micropub.biology.000823. PMID: 37215640; PMCID: PMC10199339.
Iyer VJ, Osman MA (2023). Haldol Targets IQGAP1 Pathway and Promotes Novel Partner Interactions in Glioblastoma Cell Lines. MicroPubl Biol. 2023 May 8;2023:10.17912/micropub.biology.000822. doi: 10.17912/micropub.biology.000822. PMID: 37228393; PMCID: PMC10203884.听
Osman听M.听A*., Antonisamy W. J, Yakirevich E. IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer. Oncotarget. 2020; 11: 2493-2511. Retrieved from听听Front听COVER PAPER
Emmanuel A. Tagoe,听Gordon A. Awandare,听Osbourne Quaye,听Richard H. Asmah,听Timothy N. Archampong,听Mahasin A. Osman,听and听Charles A. Brown (2021).听Helicobacter Pylori Variants with ABC-Type Tyrosine Phosphorylation Motif in Gastric Biopsies of Ghanaian Patients. BioMed Res. Interl 2021 6616059.听https://www.hindawi.com/journals/bmri/2021/6616059/
Tanos, B. E., Perez Bay, A. E., Salvarezza, S., Vivanco, I., Mellinghoff, I., Osman, M., Sacks, D. B., Rodriguez-Boulan, E.听IQGAP1 controls tight junction formation through differential regulation of claudin recruitment.Journal of cell science. 2015; 128 (5) : 853-862.听听
Slavica Tudzarova and Mahasin A. Osman听The double trouble of metabolic diseases: the diabetes鈥揷ancer link.听Molecular biology of the cell. 2015; 26 (18) : 3129-3139.听听
Osman MA, Sarkar FH, Rodriguez-Boulan E A molecular rheostat at the interface of cancer and diabetes.. Biochimica et biophysica acta. 2013; 1836 (1) : 166-76.听听
Osman MA, Bloom GS, Tagoe EA Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity.. Cytoskeleton (Hoboken, N.J.). 2013; 70 (7) : 349-59.听听
Wang, J-B, Sonn, R., Tekletsadik, Y. K. Samorodnitsky, D. and听Osman,听M. A.听(2009). IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway.听J Cell Sci; 122.听p.听2024-2033.听PMCID: PMC2723156.听highlighted editorially and on the cover
Rittmeyer, E. N. Daniel, S. Hsu, S. C., and听Osman, M. A. (2008). A dual role for IQGAP1 in regulating exocytosis.听J Cell Sci; 121, 391-408听听().听Highlighted editorially and on the cover.听PMID: 18216334.
Osman M An emerging role for IQGAP1 in regulating protein traffic..TheScientificWorldJournal. 2010; 10 : 944-53.听听
Books
Mahasin A. Osman听Regulation of Cytoskeleton Dynamics in Health and Disease: role of molecular switches and rheostats.听2015; : 11-62.听听
Abstracts
Osman MA听Role of Signal Dynamics in the Link Between Type 2 Diabetes and Cancer. .听Journal of the Pancreas. 2014; 15 (5) : 530.听